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Melanoma of the foot

Discussion in 'General Issues and Discussion Forum' started by NewsBot, Oct 30, 2009.

  1. NewsBot

    NewsBot The Admin that posts the news.

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    Management of primary cutaneous melanoma of the hands and feet: a clinicoprognostic study.
    Rex J, Paradelo C, Mangas C, Hilari JM, Fernández-Figueras MT, Ferrándiz C.
    Dermatol Surg. 2009 Oct;35(10):1505-13.
     
  2. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Melanoma of the feet: misdiagnosed and misunderstood.
    Albreski D, Sloan SB.
    Clin Dermatol. 2009 Nov-Dec;27(6):556-63.
     
  3. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Development of a practical guide for the early recognition of malignant melanoma of the foot and nail unit.
    Bristow IR, de Berker DA.
    J Foot Ankle Res. 2010 Sep 28;3(1):22.
     
  4. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Clinical guidelines for the recognition of melanoma of the foot and nail unit
    Ivan R Bristow, David AR de Berker, Katharine M Acland, Richard J Turner and Jonathan Bowling
    Journal of Foot and Ankle Research 2010, 3:25doi:10.1186/1757-1146-3-25
     
  5. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Prognostic variables and surgical management of foot melanoma: review of a 25-year institutional experience.
    Rashid OM, Schaum JC, Wolfe LG, Brinster NK, Neifeld JP.
    ISRN Dermatol. 2011;2011:384729.
     
  6. NewsBot

    NewsBot The Admin that posts the news.

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    1
    A rare form of melanoma masquerading as a diabetic foot ulcer: a case report.
    Thomas S, Meng YX, Patel VG, Strayhorn G.
    Case Report Endocrinol. 2012;
     
  7. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Malignant melanoma on the foot
    Hashmi, Farina
    Dermatological Nursing, Volume 11, Number 3, September 2012 , pp. 40-45(6)
     
  8. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Melanoma - The wolf in sheep's clothing
     
  9. NewsBot

    NewsBot The Admin that posts the news.

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    Surgical treatment of primary melanoma.
    Bennàssar A, Ishioka P, Vilalta A.
    Dermatol Ther. 2012 Sep;25(5):432-442.
     
  10. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Malignant melanoma of the foot in patients with diabetes mellitus--a trap for the unwary.
    Hussin P, Loke SC, Noor FM, Mawardi M, Singh VA.
    Med J Malaysia. 2012 Aug;67(4):422-3.
     
  11. blinda

    blinda MVP

    Pt has provided permission to share this:


    [​IMG]

    Pt was advised by GP that the `black is only fungus....`:bang:

    I referred for punch biopsy and results were subungual melanoma with Hutchinson sign. Gotta keep an eye out.
     
  12. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Clinical and histological features of melanoma in adult nigerians.
    Atanda AT, Umar AB.
    West Afr J Med. 2012 Jul-Aug;31(3):149-53.
     
  13. NewsBot

    NewsBot The Admin that posts the news.

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    Press release:
    Gene linked to worse outcomes for melanoma
     
  14. NewsBot

    NewsBot The Admin that posts the news.

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    Cutaneous malignant melanoma: clinical and histopathological review of cases in a Malaysian tertiary referral centre.
    Pailoor J, Mun KS, Leow M.
    Malays J Pathol. 2012 Dec;34(2):97-101.
     
  15. NewsBot

    NewsBot The Admin that posts the news.

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    Targeted therapy in melanoma.
    Kudchadkar RR, Smalley KS, Glass LF, Trimble JS, Sondak VK.
    Clin Dermatol. 2013 Mar;31(2):200-8.
     
  16. NewsBot

    NewsBot The Admin that posts the news.

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    Press release:
    Aspirin may lower melanoma risk
     
  17. NewsBot

    NewsBot The Admin that posts the news.

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    In situ subungual melanoma: digit salvaging clearance.
    Chow WT, Bhat W, Magdub S, Orlando A.
    J Plast Reconstr Aesthet Surg. 2013 Feb;66(2):274-6.

     
  18. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Monell-Led Research Identifies Scent of Melanoma
     
  19. NewsBot

    NewsBot The Admin that posts the news.

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    Patient presenting with left arm complaint has hidden melanoma on the sole.
    Prath PE, Aires DJ, Squires S.
    Dermatol Online J. 2013 Jan 15;19(1):13.
    Full text
     
  20. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Single injection may revolutionize melanoma treatment, Moffitt study shows
    Injectable dye shows promise as possible immunotherapy option for melanoma patients
     
  21. Admin2

    Admin2 Administrator Staff Member

    Melanoma

    Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes.[1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma).[1][2] In women, melanomas most commonly occur on the legs; while in men, on the back.[2] Melanoma is frequently referred to as malignant melanoma. However, the medical community stresses that there is no such thing as a 'benign melanoma' and recommends that the term 'malignant melanoma' should be avoided as redundant.[7][8][9]

    About 25% of melanomas develop from moles.[2] Changes in a mole that can indicate melanoma include increase—especially rapid increase—in size, irregular edges, change in color, itchiness, or skin breakdown.[1]

    The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of the skin pigment melanin.[2][10] The UV light may be from the sun or other sources, such as tanning devices.[2] Those with many moles, a history of affected family members, and poor immune function are at greater risk.[1] A number of rare genetic conditions, such as xeroderma pigmentosum, also increase the risk.[11] Diagnosis is by biopsy and analysis of any skin lesion that has signs of being potentially cancerous.[1]

    Avoiding UV light and using sunscreen in UV-bright sun conditions may prevent melanoma.[2] Treatment typically is removal by surgery of the melanoma and the potentially affected adjacent tissue bordering the melanoma.[1] In those with slightly larger cancers, nearby lymph nodes may be tested for spread (metastasis).[1] Most people are cured if metastasis has not occurred.[1] For those in whom melanoma has spread, immunotherapy, biologic therapy, radiation therapy, or chemotherapy may improve survival.[1][12] With treatment, the five-year survival rates in the United States are 99% among those with localized disease, 65% when the disease has spread to lymph nodes, and 25% among those with distant spread.[4] The likelihood that melanoma will reoccur or spread depends on its thickness, how fast the cells are dividing, and whether or not the overlying skin has broken down.[2]

    Melanoma is the most dangerous type of skin cancer.[2] Globally, in 2012, it newly occurred in 232,000 people.[2] In 2015, 3.1 million people had active disease, which resulted in 59,800 deaths.[5][6] Australia and New Zealand have the highest rates of melanoma in the world.[2] High rates also occur in Northern Europe and North America, while it is less common in Asia, Africa, and Latin America.[2] In the United States, melanoma occurs about 1.6 times more often in men than women.[13] Melanoma has become more common since the 1960s in areas mostly populated by people of European descent.[2][11]

    1. ^ a b c d e f g h i j k l m "Melanoma Treatment – for health professionals". National Cancer Institute. 26 June 2015. Archived from the original on 4 July 2015. Retrieved 30 June 2015.
    2. ^ a b c d e f g h i j k l m n World Cancer Report (PDF). World Health Organization. 2014. pp. Chapter 5.14. ISBN 978-92-832-0429-9. Archived (PDF) from the original on 30 May 2014.
    3. ^ Goldstein BG, Goldstein AO (April 2001). "Diagnosis and management of malignant melanoma". American Family Physician. 63 (7): 1359–68, 1374. PMID 11310650.
    4. ^ a b "SEER Stat Fact Sheets: Melanoma of the Skin". NCI. Archived from the original on 6 July 2014.
    5. ^ a b Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. (GBD 2015 Disease Injury Incidence Prevalence Collaborators) (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
    6. ^ a b Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. (GBD 2015 Mortality Causes of Death Collaborators) (October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
    7. ^ Schwartzman RM, Orkin M (1962). A Comparative Study of Diseases of Dog and Man. Springfield, IL: Thomas. p. 85. The term 'melanoma' in human medicine indicates a malignant growth; the prefix 'malignant' is redundant.
    8. ^ Bobonich M, Nolen ME (2015). Dermatology for Advanced Practice Clinicians. Philadelphia: Wolters Kluwer. p. 106. The term malignant melanoma is becoming obsolete because the word 'malignant' is redundant as there are no benign melanomas.
    9. ^ Farlex Partner Medical Dictionary. 2012. Archived from the original on 10 June 2022. Retrieved 4 March 2021. Avoid the redundant phrase malignant melanoma.
    10. ^ Cite error: The named reference SunM was invoked but never defined (see the help page).
    11. ^ a b Azoury SC, Lange JR (October 2014). "Epidemiology, risk factors, prevention, and early detection of melanoma". The Surgical Clinics of North America. 94 (5): 945–62, vii. doi:10.1016/j.suc.2014.07.013. PMID 25245960.
    12. ^ Syn NL, Teng MW, Mok TS, Soo RA (December 2017). "De-novo and acquired resistance to immune checkpoint targeting". The Lancet. Oncology. 18 (12): e731–e741. doi:10.1016/s1470-2045(17)30607-1. PMID 29208439.
    13. ^ "USCS Data Visualizations". gis.cdc.gov. Archived from the original on 17 March 2020. Retrieved 7 March 2020. Need to select "melanoma"
     
  22. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Malignant skin tumors in benin city, South-South, Nigeria.
    Forae GD, Olu-Eddo AN.
    Oman Med J. 2013 Sep;28(5):311-5.
     
  23. NewsBot

    NewsBot The Admin that posts the news.

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    Why Is Melanoma So Metastatic?
    Russell R. Braeuer et al
    Pigment Cell & Melanoma Research; Accepted Article
     
  24. NewsBot

    NewsBot The Admin that posts the news.

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    The Importance of Wound Biopsy in the Accurate Diagnosis of Acral Malignant Melanoma Presenting as a Foot Ulcer
    Natalie C. Yin, Mariya Miteva, Donald S. Covington, Paolo Romanelli, Olivera Stojadinovic,
    International Journal of Lower Extremity Wounds December 9, 2013
     
  25. toughspiders

    toughspiders Active Member

    Wasn't there talk of Bob Marley succumbing to Acral Lentiginous Melanoma ? Dont know how true it is?
     
  26. Craig Payne

    Craig Payne Moderator

    Articles:
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    indeed:
    http://en.wikipedia.org/wiki/Bob_Marley#Illness_and_death
     
  27. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Treatment outcomes of advanced stage malignant melanoma in hand and foot after amputation in korean patients.
    Cho K, Jung ST.
    Clin Orthop Surg. 2013 Dec;5(4):314-20.
     
  28. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    New diagnostic and therapeutic techniques show potential for patients with metastasized melanoma
     
  29. NewsBot

    NewsBot The Admin that posts the news.

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  30. NewsBot

    NewsBot The Admin that posts the news.

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    Acral lentiginous melanoma: indolent subtype with long radial growth phase.
    Kim JY1, Choi M, Jo SJ, Min HS, Cho KH.
    Am J Dermatopathol. 2014 Feb;36(2):142-7.
     
  31. NewsBot

    NewsBot The Admin that posts the news.

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    A Case of Malignant Melanoma with In-Transit Metastasis That Responded to Intravenous Infusion of Interferon-β.
    Arima M, Iwata Y, Morita Y, Kobayashi T, Sasaki R, Suzuki K, Matsunaga K.
    Case Rep Dermatol. 2014 Mar 7;6(1):74-9.
     
  32. NewsBot

    NewsBot The Admin that posts the news.

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    Comparison of Anatomic Locations of Cutaneous Melanoma in Men and Women: A Population-Based Study in France.
    Chevalier V, Barbe C, Le Clainche A, Arnoult G, Bernard P, Hibon E, Grange F.
    Br J Dermatol. 2014 Apr 11
     
  33. NewsBot

    NewsBot The Admin that posts the news.

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    Vaccine improves survival for melanoma
     
  34. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Exact outline of melanoma could lead to new diagnostic tools, therapies
    05/08/2014
     
  35. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Myriad myPath melanoma test improves the reliability of melanoma diagnosis
    Pivotal clinical validation data presented at the 50th ASCO Annual Meeting
     
  36. NewsBot

    NewsBot The Admin that posts the news.

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    Malignant Melanoma Presenting as a Nonhealing Heel Ulceration.
    Fussell JN, Troutman DL, Hossler E, Agarwal S.
    J Am Podiatr Med Assoc. 2014 May;104(3):295-297.
     
  37. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    New UK study helps scientists understand melanoma development
     
  38. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    FDA approves new melanoma drug that turns on the immune system to fight deadly cancers
    A ‘game changer,’ says UCLA’s Dr. Antoni Ribas, the study’s principal investigator

     
    Last edited by a moderator: Sep 22, 2016
  39. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    Myriad myPath™ Melanoma improves diagnosis and treatment plans
    New prospective clinical utility data presented at the ASDP Annual Meeting
     
  40. NewsBot

    NewsBot The Admin that posts the news.

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    Press release:
    FDA approves Opdivo for advanced melanoma
     
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