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New drugs for neuropathic pain

Discussion in 'Diabetic Foot & Wound Management' started by admin, Nov 24, 2004.

  1. admin

    admin Administrator Staff Member


    Members do not see these Ads. Sign Up.
    Press release: Approvals for Expensive New Therapies Will Drive Key Neuropathic Pain Markets to Double Over the Next Decade
    Full press release..
     
    Last edited: Nov 24, 2004
  2. podrick

    podrick Active Member

    anodyne

    has anyone had any success using led therapy with the anodyne modality for neuropathy patients.
     
  3. wayne@originbiomed.com

    wayne@originbiomed.com Welcome New Poster

    neuropathic pain. Have you tried Neuragen?

    Neuragen RL is a proprietary natural medication for treating neuropathic pain by topical application.

    Extensive use of Neuragen RL, including a controlled clinical trial, demonstrates its effectiveness as a topical analgesic which quickly relieves neuropathic pain in a variety of situations without harmful side effects. Most topical analgesics now on the market are useful for muscle aches and related inflammatory pain, but not for neuropathic pain – Neuragen RL helps for pain the others don’t touch. Neuragen RL does not numb the area of application and can be applied repeatedly. The key active ingredient of Neuragen RL is a purified variety of geranium oil, carefully isolated from years of clinical testing.

    http://www.originbiomed.com/pdf/Neursurv_res_Oct04.pdf


    http://www.originbiomed.com/pdf/TempReliefGeraniumOil_AJM.pdf
     
  4. sandra.jones

    sandra.jones Member

    Treatment of neuropathy

    Has anyone has success using acupuncture for the treatment of painful peripheral neuropathy? I feel for patients who are already on multiple medications its a useful treatment option to offer before adding in yet another tablet.
    Sandra
     
  5. John Spina

    John Spina Active Member

    Sandra,you came upwith a good idea.Accupuncture is a good adjunct therapy which a lot of doctors(me included)underutilize.I am trying cymbalta for the pain-1 60 mg tablet q24h.I try the antiepileptics with fair results.I also go with capsaicin which is a topical analgesic derived from a hot pepper plant.This works by depleting substance P.
     
  6. Tully

    Tully Active Member

    I also go with capsaicin which is a topical analgesic derived from a hot pepper plant.This works by depleting substance P.

    my patients tell me they can only purchase this topically in WA in combination with topical glucosamine...a GP reportedly also told a patient it was available by prescription in WA either...anyone else has any luck getting it?
     
  7. Tully

    Tully Active Member

    Size of study group

    Perhaps when the study group is of a more decent size to draw conclusions
    (ie 2900 not 29) I will feel more comfortable with the claims made
     
  8. John Spina

    John Spina Active Member

    Today I had a fellow with a severely painful case of diabetic neuropathy.I wanted to start him on cymbalta.Then I saw that his liver enzymes(SGOT and SGPT) were markedly elevated.I did not put him on that.Be careful regarding the newer meds with people with liver problems.
     
  9. John Spina

    John Spina Active Member

    Accupuncture can be a very useful therapy for people who have "gone through the mill" regarding treatments for diabetic neuropathy.It seems that this is a very trying malady to treat.
     
  10. Gibby

    Gibby Active Member

    I know some cases of accupuncture and accupressure helping difficult neuropathic pain. I also have experience with a Dr. Lee at LSU's Pennington Biomedical Research Institute/ Neuromedical Center in Baton Rouge, LA. He has a study and treatment program using Tai-Chi for treatment of neuropathic pain. I have a few patients who have benefitted from this Tai-Chi program. -John

    Sorry, this appears to be an old discussion--
    Still relevant, though. Neuropathy is difficult to treat successfully.
     
    Last edited: Feb 6, 2009
  11. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Press Release:
    Phase II Results For GSK1838262 (XP13512) Reported For Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
    29 Apr 2009
     
  12. pgcarter

    pgcarter Well-Known Member

    I know a rehab/occupational physician who does a lot of work with long term pain. He recommends use of "goanna" ointment, which is a non-prescription analgesic cream that has a fair dose of capsaicin in it. A cheaper way to access whatever benefit capsaicin can provide.
    regards Phill
     
  13. GarethNZ

    GarethNZ Active Member

    I have been using Acupuncture for Diabetic and non-Diabetic neuropathy. After the 1st session in most cases there has been some change. Within 3 sessions there has been significant change in the pain and less numbness reported as well.

    There are 5 points in the foot and 3 on the leg that I find useful, only using these one leg only - this affects both legs though.

    Is there anyone else who is having some success with Acupuncture?
     
  14. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    The effect of Neuragen PN(R) on neuropathic pain: a randomized, double blind, placebo controlled clinical trial.
    Li L.
    BMC Complement Altern Med. 2010 May 20;10(1):22.
     
  15. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Press Release:

    ARCION THERAPEUTICS’ TOPICAL GEL CANDIDATE, ARC‐4558, DEMONSTRATES SIGNIFICANT
    PAIN REDUCTION IN PHASE 2b TRIAL FOR PAINFUL DIABETIC NEUROPATHY (PDN)

     
  16. Hoppo

    Hoppo Member

    Re: Treatment of neuropathy

    Yes Sandra I have had some success using acupuncture, with some patients rebooking in specifically for a repeat Tx. Others have found no benefit at all and a small few have freaked out. If they suffer from anxiety I now give acupuncutre a wide berth unless they specifically ask for it.
    Hope this helps Shaun
     
  17. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
    Nanna B Finnerup, MD, Prof Nadine Attal, MD, Simon Haroutounian, PhD, Ewan McNicol, MS, Prof Ralf Baron, MD, Prof Robert H Dworkin, PhD, Prof Ian Gilron, MD, Maija Haanpää, MD, Prof Per Hansson, MD, Prof Troels S Jensen, MD, Peter R Kamerman, PhD, Karen Lund, MD, Prof Andrew Moore, DSc, Prof Srinivasa N Raja, MD, Prof Andrew S C Rice, MD, Prof Michael Rowbotham, MD, Emily Sena, PhD, Prof Philip Siddall, MD, Prof Blair H Smith, MD, Prof Mark Wallace, MD
    The Lancet Neurology; Volume 14, No. 2, p162–173, February 2015
     
  18. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    This clinical trial was just registered:
    The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy
     
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