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Does anybody know where I can source some Magenta Paint in the UK/Ireland. My local pharmacist is no help.

Justin

Do anyone know where I can source Magenta Paint in the UK - the local pharmacists are no help.

Justin

Please don't start new threads on the same topic - I have merged your two threads into one.

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As far as I am aware Magenta Paint has been generally withdrawn from use due to the potentially carcinogenic effects (gentian violet, acriflavine and other wondrous coloured solutions left with it). There was also a study in the British Journal of Dermatology in 1978 by Rogers, Burrows and Neil which indicated that the phenol within the solution could be absorbed percutaneously. This was generally considered to be not a good thing.

Did you have any particular therapeutic purpose in mind? Perhaps the good folk of this forum might be able to suggest alternatives.

cheers,

Felicity
(who is, admittedly, from Australia and acknowledges the situation re availability might be different in the UK)

Castellani or Magenta paint -- Castellani paint acquired its name from an Italian physician, Sir Aldo Castellani (1877-1971); it is also called carbolfuchsin paint. Is a fungicidal and bactericidal liquid with an anesthetic effect on the skin and an antiseptic and drying agent. Is a magenta liquid that stains the skin red.

The paint mixture is composed of resorcinol (8 g), acetone (4 mL), magenta (0.4 g), phenol (4.0 g), boric acid (0.8 g), industrial methylated spirit 90% (8.5 mL), and water (100 mL). Can be prepared in colorless form.

Adult Dose Apply daily for 2 wk usually qhs
Pediatric Dose <10 years: Do not administer
>10 years: Administer as in adults

Contraindications Documented hypersensitivity
Interactions Phenols may cross react with resorcin, cresols, and hydroquinone
Pregnancy C - Safety for use during pregnancy has not been established.
Precautions Guard against spilling; can stain clothing and skin; may be toxic in children because of phenol content; may cause irritation, especially in diaper or other intertriginous regions; may be toxic in dilute solutions if used over large areas.

The Rogers paper related to infants - if you're worried about phenol absorption then maybe the good folk could also suggest an alternative for matrix phenolisation. I find that some of these wonderfully coloured preperations that you mentioned work far more effectively than their modern day counterparts and the patients find the colours pretty funky.

If I lived closer to you Felicity then I could probably call APC on (02) 9793-1161

Justin


Australian Pharmacy Compounding (APC) - "is a custom-built compounding pharmacy approved by the Pharmacy Board of NSW. "

"Dermatological prescriptions are one of our most commonly compounded products. Whether it be the addition of an active ingredient into a simple vehicle like a cream or lotion, or the formulation of a customised product to meet a patient's unique needs, we have the knowledge and capability to ensure patients receive the best results.

Commonly compounded prescriptions for dermatology include products for hyperpigmentation, eczema, psoriasis, acne, fungal infections, and other miscellaneous infections.

The following preparations for dermatology / skin care are currently available:

Tacrolimus 0.03% or 0.1% Cream & Ointment

Clobetasol Propionate 0.05% Cream, Ointment & Scalp Lotion

Compound Hyperpimentation Cream

Castellani's Paint

Potassium Permangante (Condie's Crystals)

Methoxysalen Cream

Silver Nitrate Solution

Well, Justin, I feel appropriately slapped down. Thanks for all the information (I should have had a better look in Le Rossignol or Read's - but the dust would have annoyed me). Good luck in your search.

Hi Blarney,

Now don't build your hopes up but I used to use Gentian Violet and Malachites green and I'm sure I had Magenta red as well? I used them in the late 1970's for recovering fingerprints from adhesive tape etc.

They were all taken off the Chemist's shelves as Felicity has mentioned as a potential carcinogenic.

Is Magenta paint back? It did have an anaesthetic effect when you spilt a couple of drops on your finger. The acetone was enough to put anyone to sleep I expect? I assume you have checked for safety here in the UK.?

This maybe a wild goose chase because I haven't dealt with this firm in years but worth a try if you are desperate! Used to be very helpful from here,

Northern Biological Supplies Ltd.
Microslide & Microtechnique Specialists,
3,Betts Avenue,
Martlesham Heath,
Ipswich.
IP5 3HR.
Tel. 01473 623995/252616
www.microscopy-uk.org.uk/index.html

Hopefully if they can not help they will point you in the right direction?

Regards,

Colin.

PS. I found my way to the www. address from the original address. Worth a read but I would use the telephone number first? They are ringing out but it is Bank Holiday Monday, What am I doing here talking to you!!!