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Cognitive function is not associated with recurrent foot ulcers in patients with diabetes mellitus and neuropathy.
Kloos C, Hagen F, Lindloh C, Braun A, Leppert K, Müller N, Wolf G, Müller UA. Diabetes Care. 2009 Feb 24. [Epub ahead of print]
Quote:
Research Design and Methods: This single centre prospective study assessed the association of cognitive function and risk for ulcer relapse in 59 patients with diabetes mellitus (age 65.1 years, diabetes duration 16.5 years, HbA1c 7.4%), peripheral neuropathy and a history of foot ulceration. Premorbid and current cognitive functions were measured (multiple choice vocabulary test (Lehrl), Number-Symbol-Test, Mosaic-Test HAWIE-R and Trail-Making-Test A and B (Reitan)). Prevalence of depression was evaluated retrospectively (diagnoses in patient files, use of antidepressive medication). Patients were re-examined after 1 year.
Results: 3 (5%) patients died during follow-up (1 of sepsis, 2 of heart problems). The remaining 56 patients developed 27 (48%) new foot ulcerations (78% minor lesions Wagner stadium 1). Characteristics of patients with and without ulcer relapse were not different. In binary logistic regression cognitive function is not predictive of foot re-ulceration.
Conclusion: Cognitive function is not an important determinant of foot re-ulceration.
Cognitive function is not associated with recurrent foot ulcers in patients with diabetes mellitus and neuropathy
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