Testosterone injection improved diabetic foot complication

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Testosterone injection improved diabetic foot complication

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28th March 2009, 01:54 PM

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Testosterone injection improved diabetic foot complication

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Improvement of the diabetic foot upon testosterone administration to hypogonadal men with peripheral arterial disease. Report of three cases
Svetlana Kalinchenko , Alexandr Zemlyanoy and Louis J Gooren
Cardiovascular Diabetology 2009, 8:19doi:10.1186/1475-2840-8-19

Quote:

Background
Lower extremity complications (neuropathy, ulceration, infection, and peripheral arterial disease) are common in diabetes mellitus. There is an inverse relation between plasma testosterone and insulin sensitivity, type 2 diabetes mellitus and HbA1c concentrations.

Methods
We report the beneficial effects of administration of testosterone to three men with a diabetic foot whose serum testosterone was subnormal.

Results
Upon normalization of serum testosterone there was an improvement of hyperglycemia, a decrease of leukocytes and of fibrinogen levels, an increase of antithrombin III activity and of tissue oxygen pressure. The wound showed granulation.

Conclusion
Beneficial effects of administration of testosterone to hypogonadal with a diabetic foot may be due to improved vascularization and to anti-inflammatory action.

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31st March 2009, 08:15 AM

kitos

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Re: Testosterone injection improved diabetic foot complication

Interesting posting NewsBot !

Does this now mean that I will have to give a 'fasting' sperm sample on top of HbA1C blood to see if my testosterone level is high enough?

Great, another stick to get beaten up with by diabetic nurses

Mind you will make a nice change to have low levels !

Nick

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