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Isotretinoin - Ingrowing toe nails

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  #1  
Old 4th July 2009, 12:04 AM
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Default Isotretinoin - Ingrowing toe nails

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I attended to a patient who was receiving acne treatment.

His complaint, an area of inflammation to the medial sulci of the hallux with hypergranulation tissue. Obviously initial thought ingrowing toe nail. His mother then goes on to tell me. That his consultant asked him if he was suffering with ingrowing toe nails. He proceded to tell her that they are a side effect of the drug.

This is a new one on me. I read that it can have a drying effect on the skin and the nails. I can see how it could make the edges of the nail flaky and split and therefore irritate or grow in....however his nail seemed to be of good texture.

Anyone know anything of this???
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Old 4th July 2009, 12:16 AM
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Craig Payne Craig Payne is offline
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Default Re: Roaccutane - Ingrowing toe nails

Its a known side affect. I recall hearing a couple of conference presentations on this. See this.
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Old 4th July 2009, 12:20 AM
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Default Re: Isotretinoin - Ingrowing toe nails

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Old 4th July 2009, 12:26 AM
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Default Re: Isotretinoin - Ingrowing toe nails

Is it noted in the literature that comes with the drug Craig?

The aritcle states it can cause paronychia, unless i misinterpreting it. How does it cause an ingrowing nail? It is a true o/c or is it inflammation caused by the drying effect on the skin, or does it cause the nail to grow differently?

My patient asked if he came off the drug would it go away?

Sorry for the barrage of q's???
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Old 4th July 2009, 12:34 AM
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Default Re: Isotretinoin - Ingrowing toe nails

Hopefully someone who knows more about this than me will respond, but there is the link I posted above (this - scroll down to picture) and this Google search
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Old 4th July 2009, 12:40 AM
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Default Re: Isotretinoin - Ingrowing toe nails

Yeah thanks Craig, I read it.

Im guessing now that what we see if the clinic may be paranycia and not an ingrowing nail????

Begs the question of whether nail surgery would be a fruitless exercise

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