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Hi
Can anyone suggest a topical cream to aid minor lesions to heal? Cuts abrasions blisters.
If there is such a thing.
Or is the lesion best irrigated in saline,covered and nature take its course.
Germolene springs to mind an over the counter all singing all curing cream???
Thanks in advance
Ian

is this a joke?

So very sorry i have obviously missed a fundamental principal for my question to be thought of as a joke. Laughs on me eh?
I hoped only to be ignorant for a short while maybe i shall be ignorant for longer.
I stupidly assumed chemicals may assist the healing process.
Would anyone be so good as to point me in the right direction?
Thank you
Ian

Hi Ian, try morhulin nappy rash cream on scratches and grazes (no!, that's not a joke) it contains cod liver oil (oleum morrhuae - hence the name) and zinc oxide. Fatty acid derivatives from cod liver oil are used in venous and ligament sclerotherapy / prolotherapy to stimulate cytokine expression, an inflammatory cascade and subsequent collagen formation in the ECM therefore improving the 'scaffolding' in damaged dense connective tissue, indeed all tissue.

The specific cod liver oil derivitive used in sclerotherapy / prolotherapy is morrhuate sodium which is high in arachidonic acid. This metabolises via the cox 1 and 2 pathways to produce thromboxanes and prostaglandins which are both proinflammatory mediators and via the lipoxygenase pathway to produce leukotrines which are also pro - inflams. In other words, it kick - starts healing by irritating the site.

Zinc, of course is the metallic bit of Matrix Metalloproteins, so is essential in a tissue healing situation.

There is nothing new under the sun, Unguentum Zinci Morrhuatis BPC was a popular minor wound healer in the 1930's.

Kind Regards,

Martin

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Darn it Jim, I'm just an old country Chiropodist - not a miracle worker

I simply suggest that patients "keep it greasy". It has been shown that a moist environment with low bacterial load heals faster. I recommend polysporin ointment under occlusion. In the past I used neosporin (triple abx ointment) but found a few patients allergic to the neomycin component- hence the switch to polysporin.

Hi
Thanks to all for the contributions.
Ian