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Hi all,
We had a rep visit our department this afternoon to show us the Arginine + nutrition supplements available now. Apparantly the Arginine-only powders are easier for a patient with diabetes to incorporate into their diet, but they had no data except that for hospital pressure ulcers and that was with the full strength supplement (+zinc +vitC)
My questions:
Has anyone had some experience using these, and how did they go?
Who purchased the supplements - the patients?
On a similar note, what nutritional info or support do you provide for patients in your Ulcer/High Risk Foot Clincs? We have tried and failed to get a dietician on our team due to staff shortages, but an education handout is hopefully not far away.
Experimentally, we demonstrated the beneficial effects of L-arginine on regulation of hyperglycemia and dyslipidemia in experimental diabetes, in addition to a positive anti-aggregating effect in platelets in animals and humans. Here, the effect of L-arginine on foot ulcers from diabetic patients was studied. Three groups of diabetic patients were included: 11 patients without ulcer received neither treatment and served as controls. Eleven patients with diabetic ulcer received the standard treatment, this group served as diabetic control with diabetic ulcer. Eleven remain patients with diabetic ulcer received 10 mM L-arginine subcutaneously on the site of the wound. Biopsy with punch number 5 on wound site comprising both ulcerative and contiguous undamaged skin were performed in all patients with ulcerative lesions before any treatment. Patients with intact skin had biopsy performed with punch number 5 on external malleolar region of right lower limb. Biopsies were examined by light and confocal microscopy utilizing histochemical and immunohistochemical methods. Initial and final blood samples were collected to determine glucose, triglycerides, total cholesterol, glycated hemoglobin (HbA(1c)), low (LDL), and high density lipoproteins (HDL). Significant differences (P < 0.05) were observed between initial and final serum glucose levels for treated patients, and initial serum glucose levels between treated and control patients without diabetic ulcer. Glycated hemoglobin, triglycerides, cholesterol, and lipoprotein levels showed no significant changes. Eight patients treated with L-arginine reached total wound healing and the remaining three who abandoned the study because of change of residence showed relevant improvement. Histochemistry and immunohistochemistry methods have shown vascular impairment in both patients with diabetic ulcer (prior to treatment) and control patients without diabetic ulcer. Our observations strongly support efficacy of L-arginine for successful wound healing of diabetic ulcers.
On a similar note, what nutritional info or support do you provide for patients in your Ulcer/High Risk Foot Clincs? We have tried and failed to get a dietician on our team due to staff shortages, but an education handout is hopefully not far away
I would be inclined to seek this information from a G.P. who has ACNEM training.
The Australian College of Nutritional and Environmental Medicine. www.ACNEM.org
This is the Australian equivalent of The Institute for Optimum Nutrition (ION). www.ion.ac.uk
ION believe in covering all aspects of health, both orthodox and alternative in order to achieve a complete understanding of the subject.
I know it is hard to get the oldies to get used to "new fangled" ideas, but with the nutrition, if you have a health food shop nearby, I would head in there get their advice,and see if they have cholorophyll, liquid preferably. It is recommended for those whose diets are lacking in natural green vegetables, it assists the healing of wounds and tissues.I prefer the chlorophyll brand Eva-K by Q Medicinals.
Similarily, wheatgrass, liquid or powder is known for its ability to stimulate tissue growth and repair.
Tahini, two tablespoons of which has equivalent protein to a large steak.It is rich in phosphorus, niacin, vitamin E, and has 10 times more calcium than cow's milk.
Herbal capsules such as Ginkgo Biloba, Hawthorn or Grape seed are meant to assist in the maintenance of peripheral circulation.
All of this of course should be checked with the G.P. and maybe a Naturopath to ensure no contraindications with current medications or diabetes ensue.
Nutritional supplements and wound healing
Re: nutritional supplements and wound healing
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